Syndrome ovarian sclerochiton

Syndrome ovarian sclerochitonSYNDROME SCLEROCYSTIC OVARIAN syndrome (Stein-Leventhal) most often occurs when the impaired function of the hypothalamic-giovianni system, dysfunction of the adrenal cortex or primary lesion of ovary (violation of the biosynthesis of steroid hormones) and is characterized by amenorrhea different duration (sometimes acyclic bleeding, hirsutism and other manifestations Verilog syndrome (see Chapter "Endocrine and metabolic diseases), obesity, infertility and enlarged polycystic-modified ovaries. Usually occurs at the age of 20-30 years. The diagnosis is based on a typical patient complaints and the detection of gynecological investigation of bilateral ovarian enlargement. The precise diagnosis by radiography of the pelvic organs with pneumoperitoneum, ultrasound and laparoscopy. Hormonal studies establish several high content of 17-ketosteroids (up to 20 mg/day), and androstenediol. Tests of functional diagnostics indicate anovulation. To avoid the syndrome of adrenal origin using a sample with dexamethasone (1 mg drug 2 times a day for 3-5 days), which detect the decrease in the concentration of 17-ketosteroids in the urine. Treatment. They often resort to wedge resection of the ovaries. The operation is performed after curettage of the uterus (the removal of pathologically altered endometrium). Attempt treatment with drugs that stimulate ovulation (clomiphene). The prognosis is usually favorable - restoration of normal menstrual cycle after surgery in 50-60% of patients; pregnancy occurs less frequently..

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